Body stages Stage 2 of 11

4–12 h

Early fast

Insulin has fallen to its baseline. The liver is releasing stored sugar, and already making new glucose from other sources.

Measured in humans, HighFree

What studies measured

Insulin back to baseline; gluconeogenesis already about half of glucose output, 64% averaged over the first 22 hours.

How it may feel

Hunger, if it comes, follows your usual mealtimes.

What to do

Water to thirst. If your fast began after an evening meal, most of this window is sleep.

Sources

  1. Rothman 1991Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR. Science, 1991.
  2. Deru 2021The Effects of Exercise on β-Hydroxybutyrate Concentrations over a 36-h Fast: A Randomized Crossover Study. Med Sci Sports Exerc, 2021.

What studies measured in healthy adults, not a reading of your own body. Stop and seek help if you feel unwell; the signs to stop for are listed under Stop signs on the safety page.

Nesteia is in testing on iPhone and not yet on the App Store.

Free: every daily window, and plans and stages to 36 h. Pro from £4.99 a month at launch.