Body stages Stage 3 of 11

12–18 h

Fat mobilisation

Fat is being released from stores in larger amounts. Ketone levels are usually still low at this point.

Measured in humans, HighFree

What studies measured

Insulin-to-glucagon ratio markedly reduced; free fatty acids rising; ketones still near baseline.

How it may feel

Mealtime hunger that passes.

What to do

Water to thirst. A 16-hour window usually ends here, and that is fine.

Sources

  1. Deru 2021The Effects of Exercise on β-Hydroxybutyrate Concentrations over a 36-h Fast: A Randomized Crossover Study. Med Sci Sports Exerc, 2021.
  2. Service and O'Brien 2005Increasing serum betahydroxybutyrate concentrations during the 72-hour fast: evidence against hyperinsulinemic hypoglycemia. J Clin Endocrinol Metab, 2005.
  3. Ho 1988Fasting enhances growth hormone secretion and amplifies the complex rhythms of growth hormone secretion in man. J Clin Invest, 1988.

What studies measured in healthy adults, not a reading of your own body. Stop and seek help if you feel unwell; the signs to stop for are listed under Stop signs on the safety page.

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